Nanotechnology in Drug Delivery - Heart Disease


Nanoparticles that are both synthetic HDL and contain a MRI different agent (iron oxide). The researchers are now conducting animal studies to determine how well the artificial HDL (high density lipoprotein) treats arterial plaque. Nanoparticle that can deliver drugs to tablet on the wall of an artery. They attach a protein called a peptide to a nanoparticle, which then binds with the surface of the plaque. While white blood cells are supposed to protect us from harmful intruders, when they attack LDL molecules they can actually cause plaque deposits on artery walls. Researchers at Rutgers have established a nanoparticle called a nanolipoblocker that is designed to attach itself to white blood cells to block them from attacking LDL cholesterol molecules. Nanoparticles that target proteins common to blood clots have been developed to deliver bismuth to clots and unstable plaque in the bloodstream.



 


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